Background: the popularity of herbal supplements has grown significantly in recent years. However, we have limited knowledge relating to why pregnant women use Integrative Medicine) and how this may relate to the provision of maternity care. Objective: This study aimed to assess the prevalence of the use of herbal medicine during pregnancy in El-Mahsama village, to find out the most common indications for which pregnant women use herbal medicine and to identify the most frequently consumed herbal medicine during pregnancy. Methods: This is a cross sectional descriptive study was conducted on 252 pregnant women attending antenatal care (ANC) clinic. Data were collected by researcher in interview with pregnant women to translate it from English to Arabic and writing the answers to avoid bias caused by illiterate women. Results: In the present study, prevalence of herbal use was 34.1%, the most frequent herbs used by participants were; Fenugreek (66.3%) followed by anise (24.4%) then peppermint (18.6%). the commonest indications of herbs were; colic (77.9%), then cough& flu (14%). On the other hand, the most common method of use was decoction (98.84%). Conclusions: The use of herbal medicine during pregnancy is a common practice in the rural area. There is a need to educate pregnant women about benefits and harms of herbal products and to train healthcare professionals on the available guidelines to herbal products used during pregnancy.