Background: Obesity has become an epidemic problem affecting both developed and developing countries. Obesity among females is an independent risk factor for both maternal and non-communicable diseases. Objectives:  To determine the prevalence of obesity and its associated risk factors among adult females. Methods:  A cross-sectional study was conducted on overweight and obese adult females attending Al-Salam family health center in Ismailia city (150 participants were randomly selected).The participants were interviewed using a structured questionnaire and their weight and height were measured to calculate the body mass index. Results: About three quarters (76%) of the study participants were overweight and obese. Among the risk factors, consumption of grains, smoking and eating while watching TV were significantly related to overweight and obesity, while hypertension and fatty liver were the most statistically significant co-morbidities (P =0.025 and 0.004 respectively). Conclusion: The study has revealed the high percentage of overweight and obesity among adult females, which may have a negative effect on the maternal health. Factors that may be associated with overweight and obesity included dietary pattern, lifestyle behaviors, and obesity co-morbidities.