The present study was designed to investigate the effect of curcumin, anise seeds levels and their interactions on growth performance and some blood parameters of broiler chicken. Two hundred and ninety seven birds were randomly assigned in (3×3) factorial design. Three curcumin levels (0, 50,100 mg/kg) and three anise ground seeds levels (0, 0.50%, 1%) in nine treatments of 33 birds each (three replicates of 11 birds each) were used.   Body weight and feed intake were recorded weekly. Body weight gain and feed conversion were calculated at the end of the experiment (42 day of age). Blood samples were obtained from birds at 21 and 42 day throughout the experiment. The results showed that chickens which were fed curcumin at level of 100 mg/kg diet achieved higher body weight, body weight gain and feed intake at 42 days of age compared to the control and level of 50 mg/kg diet. Also, the addition of anise ground seeds achieved higher body weight, body weight gain and feed intake at 42 days of age compared to the control. No significant (P<0.05) effects on feed conversion ratio were observed due to curcumin, anise ground seeds and their interactions. There were significant (P<0.05) effect due to curcumin levels on  cholesterol, LDL at 42 day. Also, There were significant (P<0.05) effect due to interactions of curcumin and anises seeds levels on HDL at 21 day and total protein, albumin, calcium cholesterol and LDL at 42 day of age. It was recommended that curcumin should be add at level of 100 or 50 mg/kg  diet plus 1% anise ground seeds to achieve the best results of growth performance and blood parameters of broiler chicken (Ross 308).