This study aimed to evaluate the effect of extruded diets (floating and sinking) on growth parameters, feed utilization and economic efficiency of Nile tilapia (Oreochromisniloticus) cultured in commercial farms. A total number of (100000) mono sex Nile tilapiafingerlings of 5.27 ± 0.01 g initial body weight in average were allotted randomly into four earthen ponds (two feddan/each). Two diets were used extruded floating diet (EFD) and extruded sinking diet (ESD), from zoo control company. The diets contained the same level of protein, carbohydrate and fat as formulation and ingredients of the experimental diets were the same. Each diet contained in average 27.37% CP and 4.57 kcal/g GE. Fish were fed pelleted extruded diet type at a rate of 3% of the total body weightand was adjusted every month intervals until harvesting. Results cleared that final mean weight and  weight gain were significantly (P≤0.05) better with EFD, while lower values were recorded with ESD, but daily gain and specific growth rate insignificantly affected by diet type.Feed intake was significantly decreased with EFD. FCR values were significantly better with EFD than ESD. Survival rates insignificantly affected and ranged between 87.23 and 92.10%. Net returns and profit index were significantly high with EFD than sinking diet. In conclusion regarding to final weight, survival rate, net returns and profit index, the EFD was best feed if served suitable environmental condition specially low wind speed and lack of birds.