The experimental work of the present study was carried out at El-Takamoly Poultry project (TPP), Fayoum Governorate, Egypt, during the period from March to July 2014. This study was undertaken to assess the dietary effects of essential oil blend (EOB), mannan oligosaccharides (MOS) and their combination on the productive performance of Golden Montazah laying hens at late egg production period. A total number of 720 laying hens plus 72 males of Golden Montaza at 56 weeks of age were allocated randomly into six treatments groups (120 hens plus 12 males), each group was equally subdivided into three replicates (40 hens plus four males). Birds were distributed into 18 pens (40 hens and four males each) in such order to have a similar mean body weight and average daily egg production. The dietary treatments used in this study were as follows: 1-Birds were fed the control diet (diet 1). 2- diet 1 + 200 mg prepared essential oil blend (PEO)/kg diet. 3-diet 1 + 100 mg commercial essential oil blend (CEO)/kg diet.  4-diet 1 + 500 mg MOS/kg diet. 5-diet 1+ 200 mg PEO + 500 mg MOS/kg diet.  6-diet 1 + 100 mg CEO + 500 mg MOS/kg diet. Results obtained could be summarized in the following: Laying hens fed diet containing 100 mg CEO + 500 mg MOS/kg diet had significantly higher values of egg production (EP%), live body weight change (LBWC) and the best feed conversion (FC), crude protein conversion (CPC) and caloric conversion ratio (CCR) during all significant periods studied, while, laying hens fed control diet had significantly lower values of EP%, LBWC and the worst FC, CPC and CCR during the same periods. No significant effect were observed for egg mass, feed intake, initial body weight, final body weight and mortality rate% during the experimental period. There were insignificant differences among all dietary treatments in carcass characteristics except, spleen%. Laying hens fed diet containing 100 mg CEO +500 mg MOS/kg diet had higher spleen% whereas, those fed control diet had lower spleen% at the end of experimental period. Laying hens fed diet containing 100 mg CEO + 500 mg MOS/kg diet had significantly higher values of lactic acid bacteria count and the lower values of total count of bacteria and E-coli, while, those fed control diet had significantly higher values of total count of bacteria and E-coli and the lower values of lactic acid bacteria count. Golden Montazah laying hens fed diet containing 100 mg CEO +500 mg MOS/kg diet gave the best economical and relative efficiency values during the period from 56 to 72 weeks. In conclusion, the results of this study indicated that feeding Golden Montazah laying hens on diets containing 100 mg CEO +500 mg MOS/kg diet improved the productive performance and relative economic efficiency values of laying hen during the period from 56 to 72 weeks of age.