An experiment was conducted to investigate the effects of increasing dietary levels of organic chromium, organic selenium and vitamin E for deleterious impacts of heat stress on broilers. A total of 120 1-d old commercial broiler chicks (Cobb) were obtained from a local hatchary. Upon arrival the chicks were divided into four groups with six replications, each of five chicks. The first group was the control group, while the second group was fed the basal diet supplemented with organic chromium (0.8 mg/kg diet), the third group was fed the basal diet supplemented with organic selenium (0.3 mg/kg diet) and the fourth group was fed the basal diet supplemented with vitamin E (200 IU/kg diet).Body weight (BW); body weight gain (BWG); feed intake (FI) and feed conversion ratio (FC) were significantly (P≤0.05) improved in treatment groups compared to the control at 21 and 42 days of the age. Red blood cell count (RBSc), hematocrit (HT), hemoglobin (Hb), hemoglobin mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), hemoglobin mean corpuscular volume (MCV) and heterophils lymphocytes ratios (H/l ratio) were significantly (P≤0.05) different in vitamin E; organic selenium and organic chromium compared to the control at 21 and 42 days of the age, but RBSc count at 21 days of age were not significant. Moreover, it has been noticed a significant (P≤0.05) increase occurrence in values of glutathione peroxidase (GPX), Super-oxide dismotase (SOD) and catalase (CAT) but the level of malondiadehyde (MDA) was significantly (P≤0.05) decreased by supplementing broiler diets with vitamin E; organic selenium and organic chromium, respectively compared to the control. Supplementing broiler diets with vitamin E; organic selenium and organic chromium improved (P≤0.05) the carcass characteristics, respectively compared to the control. However, these improvements were insignificant in abdominal fats, thymus, bersa and spleen. The present results indicate that the supplementation of diets with vitamin E; organic selenium and organic chromium, especially vitamin E, is necessary to overcome the deleterious effects of heat stress on broilers.