This study was carried out to investigate the possibility different levels of a sun dried sugarcane bagasse (SDSCB) incorporation in growing beef crossbred calves (GBCC) as non-conventional source roughage under Aswan condition governorate as a partial replacement of barely straw in diet. Three experimental group of 54 animals each with initial live body weight of about 289, 285.61 and 280.56 kg for 1st ,2nd and 3rd group were used, respectively. Sun dried sugarcane bagasse (SDSCB) mash replaced 50% plus 1.5% urea and 100% plus 3% urea of the barely straw in three groups, respectively. The study was extended for fifteen weeks. Live body weights were individually recorded in all group. Blood samples were gathered from each animal in all groups at the finishing of study for determination of certain blood biochemical indices. Results showed that treated groups (T2 and T3) recorded significant increase (P≤0.05) in dry matter intake (DMI), digestion coefficients, average daily gain, total body weight gain and better feed conversion ratio in comparing with control group. Results showed a higher (P≤0.05) water consumption recorded for animals fed bagasse plus urea in comparing with animals fed barely straw. Similar trend were detected in blood serum total protein, albumin, globulin, AST and ALT with a significant increase (P≤0.05) in the group fed the higher level of SDSCB in normal range. Economics of weight gain was also favorable (P≤0.05) for 100% bagasse plus 3%urea as compared to 0% bagasse group. In general, it may be concluded that SDSCB can be use in rations of growing beef crossbred calves (GBCC) up to the level of 100% of roughage diet.