One hundred and twenty unsexed one-day-old Cobb broiler chicks were randomly distributed into four groups (5 replicates per group) to study the effect of multienzymes and/or probiotics supplementation on productive performance and nutrients digestibility of broiler chickens. The first group was used as control and fed the basal diet without supplementation, while, chicks in the 2nd ,3rd and 4th groups were fed the basal diet supplemented with multienzymes (Avizyme at 0.20 g/kg diet), probiotics (Biacton at 0.50 g/kg diet) and multienzymes plus probiotics (0.20 g Avizyme /kg diet + 0.50g/kg Biacton), respectively. Body weight (BW), body weight gain (BWG), and feed intake (FI) were recorded. Feed conversion rate (FCR), production index and economical efficiency were calculated. At the end of the experiment a digestibility trial was carried out. Results showed that the chickens fed diet supplemented with multienzymes and probiotics during days 22-35 and 0-35 of age had significantly higher BWG and FI and better FCR followed by those fed diet supplemented with either multienzymes or probiotics compared to those fed control diet. The multienzymes and/or probiotics supplementation had significantly improved the digestibility of dry matter (DM), crude protein (CP) and ether extract (EE) compared to the control. In addition, dietary supplementation with multienzymes plus probiotics or multienzymes alone had significantly improved the digestibility of crude fiber (CF) compared to the control. Chicks fed diet supplemented with multienzymes plus probiotics had significantly better production index and economical efficiency followed by those fed diet supplemented with multienzymes or probiotics alone compared to those fed the control diet. In conclusion: multienzyme and /or probiotics are good growth stimulators to the broiler chicks and can be added together to the diet to improve productive performance and feed utilization.