The aim followed in the present paper was to evaluate physical and chemical properties of Barki and Abu-Dleek sheep leathers, tanned with different tanning materials. Fifteen sheepskins from each breed at marketing age were collected and tanned with different tanning methods; mineral with chromium salts and vegetable with quebracho or mimosa extracts. Leather properties were assessed. Abu-Dleek leathers were higher quality than Barki leathers when tanned with different tanning materials. With respect to influence of tanning method, mineral tanned leathers were higher quality than vegetable tanned leathers. Within vegetable tanned leathers, leathers tanned with quebracho extract were higher than leathers tanned with mimosa extract.