Introduction: An accurate digital impression is essential in fabrication of fixed dental prostheses. Digital dental impressions are recorded either by intraoral or extraoral scanners.  Intraoral scanners scan abutments inside oral cavity eliminating the need of fabrication of dental casts. The extraoral scanners scan physical impressions or dental casts to produce a digital model.
Objectives: The aim of this study was to compare the accuracy of digital dental models produced by two different intraoral scanners in relation to the reference cast.
Materials and Methods: This in vitro study included an original typodont simulating patient's mouth. The reference typodont model was scanned by two intraoral scanners (3shape, Dental Wings) to produce digital models from both scanners. Mesiodistal (MD) and buccolingual (BL) measurements were recorded for canines, first premolars and first molars in both maxillary and mandibular jaws by same operator in the right and left sides and compared to measurements done on reference model. P values and adjusted means were calculated. Significance was set at 5%. SPSS version 22.0 was used for statistical analysis.
Results: There was no significant difference found between the accuracies of 3shape and Dental Wings digital models (p-value = 0.97) which were <0.5mm, in comparison to the reference model. Regarding the reference teeth, the canine showed the highest accuracy (P< 0.0001).
Conclusions: The accuracy of digital models produced by the two intraoral scanners was similar with a minor level of discrepancies. Also, the canine showed the highest accuracy in the scanning procedure as it possess smooth surface.