Introduction: Osseointegration, defined as a direct structural and functional connection between ordered living bone and the surface of a load-carrying implant, is critical for implant stability and is considered a prerequisite for implant loading and long-term clinical success of endosseous dental implants.
Primary stability following implant placement is essential for osseointegration and is mainly influenced by the following main factors density, quantity of bone at the implant site and implant design.
Moreover, implant surface topography is a key factor in the achievement of osseointegration, the most common modification of implant topography is surface roughness. This is achieved by acid etching, sandblasting, or oxidization. 
Objectives: To evaluate the effectiveness of using MPM, compared to the use of bone graft alone, to assess the exact effect of each in enhancing the osteogenic differentiation and bone formation.
Materials and methods: This clinical study was performed on a total of eleven patients (14 implants), with missing mandibular posterior teeth indicated for implant restoration. Implants were placed according to manufacturer's instructions. After 3 months, final crowns were delivered. All implants were followed up for 6 months. Clinically, each patient was evaluated for pain, swelling and stability of the implant. Radiographically, cone beam computed tomography (CBCT) was used for the assessment of marginal bone level and bone density. Results:There was a significant increase in bone density from the preoperative phase to the end of the 6 months. The mean of marginal bone level loss from the preoperative period to the 3rd month was significant as well as from the preoperative period to the 6th month. One case displayed periimplantitis and mobility in the first month of follow up and hence it was removed and regarded as failure case.
Conclusions: Self osteomizing implants are a good choice for replacing missing mandibular posterior teeth with satisfactory clinical outcomes and a low incidence of complications.