INTRODUCTION: The goal of modern dentistry is to restore the patient to normal contour, function, comfort, esthetics, speech and health regardless of the atrophy, disease or injury of the stomatognathic system. Dental implant is defined as a prosthetic device alloplastic material implanted into the oral tissues beneath the mucosal or periosteal layer within the bone to provide retention and support for a fixed or removable prosthesis. OBJECTIVES: The aim of this study was to evaluate clinically and radiographically the use of calcium ion surface treated nanostructure implant system for missing maxillary anterior teeth. MATERIALS AND METHODS: Eleven patients with anterior maxillary missing tooth were treated with calcium ion nanostructure implant. An implant stability and assessment of the osseointegration progress evaluation was conducted using the resonance frequency analysis technique (Osstell) immediately after implant placement and after one and half month at the loading time. Also, radiographic investigations were performed after one and half and three months to estimate the peri-implant mean bone density. RESULTS: all of the cases showed an uneventful wound healing. Mean bone density after three months showed a statistically significant (p < 0.001) increase in its values when compared to the immediately postoperative values. Implant stability showed statistical significant difference detected clinically by Osstell. CONCLUSIONS: The calcium ion nanostructure implant system showed an adequate clinical and radiographic performance in the replacement of missing maxillary anterior teeth with and early loading protocol.