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57868

EVALUATION OF THE EFFECT OF HYALURONIC ACID MIXED WITH BIPHASIC CALCIUM PHOSPHATE ON BONE HEALING AROUND DENTAL IMPLANTS (EXPERIMENTAL STUDY)

Article

Last updated: 22 Jan 2023

Subjects

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Tags

Oral and maxillofacial surgery

Abstract

INTRODUCTION: Biphasic calcium phosphate (BCP) is very widely used as a grafting material around dental implants. The properties of such material can be enhanced by adding interpositional graft materials to enhance osteoinduction. Hyaluronic acid (HyA) is an example of osteopromoting materials that can be added to the BCP to enhance its osteoinductive properties. OBJECTIVES: Histological evaluation of using HyA with BCP on bone healing around dental implants. MATERIALS AND METHODS: This study was a split mouth design. It was conducted on 9 mongrel dogs. The dogs were allocated into two groups: Group A (Study Group): The right side of the mandible received dental implants with biphasic calcium phosphate bone graft mixed with hyaluronic acid following extraction of the mandibular third premolar. Group B (Control Group): The left side of the mandible received dental implants with biphasic calcium phosphate bone graft only following extraction of the mandibular third premolar. Dogs were sacrificed at 2, 4 and 6 weeks postoperatively. Segments containing the implant and bone graft were retrieved with adjacent bone to be prepared for histological examination using Haematoxylin and eosin stain and Trichrome stain. RESULTS: All animals survived well, and remained active and alert all over the course of the experiment. Both groups were characterized by new bone formation. The newly formed bone was more evident in association with group (A). CONCLUSIONS: HyA accelerates the onset of new bone formation when combined with BCP for bone augmentation in the treatment of osseous defects.

DOI

10.21608/adjalexu.2017.57868

Keywords

Dental implants, Biphasic Calcium phosphate, Mandible, Hyaluronic acid, osseointegration

Authors

First Name

Mostafa M.

Last Name

Shamma

MiddleName

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Affiliation

B. D. S. Faculty of Dentistry, Alexandria University

Email

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City

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Orcid

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First Name

Sherif S.

Last Name

Ayad

MiddleName

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Affiliation

Professor of Oral & Maxillofacial Surgery, Faculty of Dentistry, Alexandria University

Email

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City

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Orcid

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First Name

Riham M.

Last Name

El-dibany

MiddleName

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Affiliation

Professor of Oral & Maxillofacial Surgery, Faculty of Dentistry, Alexandria University

Email

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City

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Orcid

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First Name

Dina A.

Last Name

Nagui

MiddleName

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Affiliation

Lecturer of Oral Biology, Faculty of Dentistry, Alexandria University.

Email

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City

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Orcid

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Volume

42

Article Issue

1

Related Issue

8732

Issue Date

2017-04-01

Receive Date

2019-11-10

Publish Date

2017-04-01

Page Start

104

Page End

107

Print ISSN

1110-015X

Online ISSN

2536-9156

Link

https://adjalexu.journals.ekb.eg/article_57868.html

Detail API

https://adjalexu.journals.ekb.eg/service?article_code=57868

Order

17

Type

Original Article

Type Code

1,057

Publication Type

Journal

Publication Title

Alexandria Dental Journal

Publication Link

https://adjalexu.journals.ekb.eg/

MainTitle

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Details

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Article

Created At

22 Jan 2023