INTRODUCTION: Reconstruction of the oral supporting tissues lost by disease or trauma is essential to tooth replacement with dental implant therapy. This treatment requires evidence based augmentative procedures combined with up-to-date and current techniques. Guided bone regeneration (GBR) aims to initialize this process of alveolar ridge reconstruction by utilizing biologically active and supportive materials best coupled to the body's healing processes. The use of non resorbable, titanium membranes can achieve GBR by ensuring graft stability and space maintenance so as to ensure optimal neovascularization. OBJECTIVES: evaluate the use of I-Gen titanium membrane used with immediately placed implant replacing a posterior mandibular tooth with buccal bone defect. MATERIALS AND METHODS: This study was conducted clinically on 10 patients indicated for extraction of a posterior tooth with buccal bone defect, tooth was extracted and an immediate implant, bone graft and I gen titanium membrane were placed. Patients were evaluated clinically and radiographically by using panoramic radiograph and cone beam computed tomography (CBCT). RESULTS: In this study no severe pain was recorded postoperatively. No signs of inflammation or swelling were observed in almost all of the patients along the follow up period. Sufficient bone thickness which is a minimum of 2 mm was formed in the targeted defect with good stability of the implants after 6 months. CONCLUSIONS: I gen titanium mesh should be considered as a valuable option for GBR in small and medium sized bone defects.