Background: Vaccine hesitancy recognized as a major challenge to the effectiveness of public health strategy aimed at eradicating infectious disease. The current study aimed to assess the effect of the nursing educational intervention to control COVID-19 vaccine hesitancy among school team members. Design: Quasi experimental design was used (pre- post educational intervention). Subjects and method: Setting: The study was implemented in Beni-suef city and Benha city, Egypt.  Subjects: Simple random sample was used to select one school from each city then all participants were included according to the inclusion criteria. Sample size was 50 participants. Tools of data collection: two tools were used; Tool (1) was an interviewing questionnaire composed of two parts; the first part was personal data questionnaire to assess personal data of the participants, part two was knowledge questionnaire to assess their knowledge regarding COVID-19 vaccine and included 9 items. Tool (2) Scale composed of two parts: the first part was attitude scale to assess the attitude of participants towards the vaccine. The second part was willing scale to assess the willing of participants to take the vaccine. Results: The results indicated that; there were significant improvements regarding total level of knowledge and attitude of studied sample post the educational intervention and the average of their willing toward the COVID-19 vaccination improved significantly from 6.4±1.1 to 8.9±.8 post the intervention. Conclusion: the willing to take the vaccine of the studied sample improved post the educational intervention. Recommendations: further studies needed to increase people awareness regarding COVID-19 vaccination to build and maintain public trust in COVID-19 vaccines.