Background: Ventilator-associated pneumonia was a severe healthcare associated infectionin intensive care units. Abdominal massage is non-pharmacological nursing intervention for decreasing elevated gastric residual, vomiting frequency and abdominal distension. Gastric distension and increased gastric residual are important risks for developing ventilator-associated pneumonia. Mechanically ventilated patients who are enterally fed, abdominal massage decreases the duration of the nutrition passage through the gastrointestinal tract, induces peristaltic movement, and thus lowers intra-abdominal pressure and the risk of aspiration. Aim: Was to assess the effect of abdominal massage on Clinical Outcomes of Enterally Fed Mechanically Ventilated Patients. Method: a quasi-experimental study, purposive sample of 60 adult's patient will be enrolled sequentially into two groups, each group consists of (30) patients. Four tools were used to conduct the study. Tool I: Patient Assessment Tool, Tool II: Glasgow coma scale, Tool III: Enteral nutrition Assessment Tools which include five parts and Tool IV: Clinical Pulmonary Infection Score (CPIS) to assess Ventilator-Associated Pneumonia (VAP). Results: The present study showed that there was a significant differences found among the intervention group throughout 1st, 3rd and 7th day of follow up regarding gastric residual volume assessments score pre and one hour post abdominal massage since p= 0.000*, 0.003*, 0.000* respectively. In addition; the study showed that 6.7% of the control group had≤6 Negative VAP compared to majority 86.7% of the study group have≤6 Negative VAP in the 7thday of follow up. Conclusion: Based on the results of the current research, it can be argued that abdominal massage is beneficial on decreasing abdominal distension; nasogastric tube feeds side effects, gastric residual volume (GRV) and reducing Ventilator-Associated Pneumonia (VAP) in the study than control group. Moreover, the results established that minority of the control group have ≤6 Negative VAP compared to majority of the study group have ≤6 Negative VAP in the 7th day of follow up. Recommendations: Abdominal massage for mechanically ventilated patients with enteral nutrition should be performed as routine nursing care if not contraindicated to lower the aspiration risk and consequently Ventilator Associated Pneumonia (VAP).