Background: Team building includes wide range of activities and strategies designed for improving team performance. Its aim is to bring out the best in a team to ensure self -development, positive communication, conflict and change management skills and the ability to work closely together as a team. Objective: The aim of the study was to evaluate program about strategies of building effective work team on nursing staff performance at intensive care units. Setting: Study was conducted at five ICUs at El-Menshawy hospital affiliated to Ministry of Health, namely neurology, cardiology, medical, pediatric and neonatal. Subjects: All (n=210) nursing staff working at the five ICUs understudy divided into all (n=10) head nurses two in each ICU and all (n=200) nurses. Tool: Two tools were used; (1) nursing staff work team building knowledge questionnaire (2) nursing staff actual work team building strategies observation checklist. Results: majority of nursing staff (84.9%) had poor knowledge level for work team building, decreased to about one third had poor knowledge level post program. Preprogram majority of nursing staff (89.6%) showed either low or moderate total practice level for work team building seven strategies, changed post program to be (51.1%) of nursing staff showed high total practice level. Half of head nurses preprogram had moderate total management practice level for work team building; changed post program to equal (40%) percent of them had high and moderate total management practice level. Conclusion: Nursing staff of ICU at El-Menshawy hospital demanding for management program to develop their knowledge and practice about team building strategies. Implementing of the program actually develops their knowledge and practice. Recommendations: conducting pre-employment educational training workshops for novice nurses about effective work team building strategies. Maintain periodical orientation of nursing staff at ICU about strategies of building effective work team.