The effects of body image on self-esteem and in turn quality of life can be especially powerful during the teenage years. Aim: This study aims to assess the relationships between body image, self- esteem and quality of life among female nursing students Design: A descriptive correlation study was utilized. Setting: The study was conducted in faculty of nursing, Ain Shams University. Subject: A convenience sample of a total of 120 female nursing students. Tools: The following instruments were utilized: 1) Brief Demographic Questionnaire and Familial Profiles; 2) Body Image Questionnaire; 3) Rosenberg Self-esteem Scale; 4) World Health Organization Quality of Life (WHOQOL-BREF) Findings: Showed that there was a statistical significant relation between the studied participants' self -esteem and their age, marital status. But there was no statistical significant relation between their self -esteem and their university level, birth order, residence, parent education, family size and family income. There was a statistical significant relation between the studied participants' quality of life domains and their age, marital status university level, birth order, parent education, family size and family income. Meanwhile there was no statistical significant relation between their quality of life domains and their residence. Conclusion: more than two fifth of female nursing student under study were have low self esteem and quarter of them were have poor body image perception .also, there was a statistically significant relations between body image, self- esteem and quality of life among female nursing students under study Recommendation: nursing students need more counseling program to attain a realistic, positive perception of their body image and to overcome the negative views about their body image in order to enhance their self-esteem and different dimensions of their quality of life.