The study aims to analyze the trade relations between Egypt and the Nile Basin countries, using the econometric method by gravity model to measure the determinants of trade intensity between Egypt and the Nile Basin countries. The study also relies on the environmental analysis to determine the strengths, weaknesses, opportunities and threats of Egyptian trade relations with the Nile Basin countries. The study indicates that there is a positive relationship between the gross domestic product of Egypt and the Nile Basin countries with the trade intensity index between Egypt and the Nile Basin countries. The study concludes that there is a gap between the actual trade between Egypt and the Nile Basin countries and the hopes placed on it, and for reducing this gap requires more efforts. The intra-trade must be supported and strengthened through the development of infrastructure in the fields of transportation, energy, communications and information technology, as well as increased coordination between Nile Basin Countries in order to unify the regulations and rules governing the movement of trade.