Background: Aphthous stomatitis also known as recurrent aphthous ulcers, is a common and non-contagious infection of the mouth in otherwise healthy individuals
Objective: To study the relationship between aphthous ulcer and vitamin D and iron level in adults.
Materials and methods: Forty patients with aphthous ulcer and 20 controls were subjected to history taking, clinical examination, and laboratory investigations mainly to correlate the level of vitamin D and iron in patients with the aphthous ulcer.
Results: This study showed that vitamin D deficiency or insufficiency is insignificant in cases suffering from aphthous ulcer than normal controls. Also, the results of the study of iron level showed no statistically significant difference between both groups.
Conclusions:  No relation between aphthous ulcer and vitamin D or iron level.