Introduction: Hypertrophy of the inferior turbinate is considered as one of the major causes of chronic nasal obstruction, which sometimes doesn't respond to medical treatment and need surgery. Different surgical techniques have been described for inferior turbinate hypertrophy Aim of the work: This study aimed to compare effectiveness and safety of partial turbinectomy and coblation in reduction of hypertrophied inferior turbinate. Materials and methods: The study was conducted in the Department of ENT, Qena faculty of medicine South Valley university. Sixty patients with inferior turbinate hypertrophy were enrolled in this study. Patients were divided in two groups (A and B), each group includes 30 patients. Group A had turbinate reduction through partial turbinectomy, and group B had turbinate reduction through coblation Results: In group A: nasal obstruction was lower in post-operative than pre-operative (1.20± 0.41 vs. 7.70± 0.47), post–operative pain was grade II in 18 patients; post-operative bleeding was recorded in 3 cases. In group B: nasal obstruction was lower in post-operative than pre-operative (1.77 ±1.01vs. 7.60 ±0.50), post–operative pain was grade I in 21 patients; post-operative bleeding was recorded in 6 cases. Conclusion and significance: Partial turbinectomy is more effective than coblation as regarding improvement of nasal obstruction.