Thirteen wheat grain varieties were screened for its susceptibil­ity/resistance against lab. Insect infestation by the rice weevil, Sitophilus oryzae (L.) under non-choice method. The parameters used for evaluat­ing of the susceptibility were the growth index, weight loss (%), percent­age of damaged grains. as well as the germination of the infested sam­ples. The results showed significant differences among the tested varieties. No variety was completely resistant or immune. Gemmiza 7 and Gin 168 were the most relatively susceptible since both produced higher values of the growth index. Sohag Durum land Giza 164 were the least relatively resistant varieties. The rest varieties were intermediate. Other complementary methods for safe storage are needed.