Bean plants are subject to attack by Macrophomina phaseolina, which was isolated from different localities in Ismailia govemorate. It was frequently isolated from infected roots and less frequently from collect­ed seeds. Nebraska bean cultivar was the least susceptible: Morgan cv. was moderately susceptible, while Xera cv. was the most susceptible. 7W­choderma harzianum as a biocontrol agent and Plant guard as a biocide resulted in a great reduction in mycelia! growth of M phaseolina isolates (In vitro) and suppressed the disease in plants grown from dressed seeds or by soil drenching. The fungicides Vitavax and Rhizolex have complete­ly prevented the mycelia! growth of tested M phaseolina isolates at 50 ppm. Benlate resulted in the same level of inhibition at 100 ppm. Vitavax reduced pre, post emergence damping-off and charcoal rot disease of Xera bean cultivar followed by Rhizolex and Benlate.