Trial was carried out for primary vaccination of pigeon with different live Newcastle disease virus (NDV) vaccines at two weeks of age before and after boosting with inactivated pigeon paramyxovirus-l (PPMV-l) at four weeks. Different strains of NDV live vaccines were used, including HBl vaccine in drinking water, intraocular instillation of laSota vaccine and intramuscular injection of Komarov vaccine. For comparison, a single dose of inactivated PPMV-l vaccine was given at four weeks age without live NDV vaccine priming. The immune response of vaccinated birds was evaluated serologically using the haemagglutination inhibition test (HIT), as well as by challenge test. The obtained results revealed that, comparatively, better immune response can be achieved in pigeons primed with laSota or Komarov vaccine before and after boosting with inactivated PPMV-l vaccine. Than priming with HB1 vaccine. It was concluded that priming of pigeon squabs intraocularly with live laSota vaccine at two weeks of age is recommendable for the practice.