Two field experiments were conducted at El-Mattana Agricultural Research Station Farm at Qena Govemorate during 2001/2002 and 2002/2003 seasons to study the effect of nitrogen rates (150, 180, 210 and 240 Kg N/fed) on yield and quality of some sugar cane varieties (G.7.54/9, F.160, G.87/37 and Ph 8013). Results revealed that: Differences among varieties in sucrose, Brix and purity percentages were significant in both seasons . The variety Ph 8013 gave the highest sucrose and Brix in the first season, while G.T.54/9 gave the highest sucrose, Brix in the second season and purity percentages in both seasons. On the other hand, F.160 variety gave the lowest reducing sugar %. Regarding poi % and recoverable sugar % Ph 8013 and 6.1.54/9 gave the highest percentage of these baits in first and second seasons, respectively. F.160 gave the thickest stalks, whereas G.87/37 gave the tallest stalks in both seasons. The highest number of minable stalks/m²resulted from G.T.54/9. Regarding yield of stalks and sugar/fed., Ph 8013 outyielded the other varieties in stalk and sugar yiekl/fed. in the 1s^t season, while in the second season G.T.54/9 significantly surpassed the other varieties in sugar production. Increasing nitrogen level up to 240 kg N/fed decreased sucrose and purity percentages, while Brix increased as N level increased up to 240 kg N/fed on the other hand ,reducing sugar % was not significantly affected by N levels. The maximum pol % in cane and recoverable sugar were recorded at the lowest level of nitrogen rate (150 kg N/fed). Increasing nitrogen rate up to 240 kg N/fed increased diameter, length of stalk, number of minable cane and stalk yield (ton/ fed), while sugar yield increased as N level increased up to 240 and 180 kg N/fed in the first and second seasons, respectively. The interaction between varieties and nitrogen levels was significant in recoverable sugar and cane yield in 2^nd season, while in stalk length in both seasons. The highest cane yield per fed. was obtained from variety F.160 with 210 Kg N/fed.