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243342

PRODUCTION AND EVALUATION OF A COMBINED INACTIVATED VACCINE AGAINST FOOT AND MOUTH DISEASE AND RIFT VALLEY FEVER USING ISA25 OIL ADJUVANT

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Last updated: 24 Dec 2024

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Abstract

As a way to safe time, cost and reduction of stress on the vaccinated animals, a combined vaccine was formulated to contain FMD (0J93 Aga) strain and RVF (211501) strain , The vaccine was inactivated by binary ethylenemine (BEI) and adjuvanted with a Montanide ISA25 oil adjuvant. A comparison was held between the results of combined vaccine and FMD and RVF vaccines separately. Both single vaccines were inactivated and adjuvanted as the combined one. The achieved results indicated that the combined FMD/RVF vaccine appeared to be more potent and slightly increased in antibody titer than monovalent either RID or RVF vaccine. The antibody titers measured for 40 weeks post vaccination in the three used vaccines as measured by different serological techniques. At the same time, the two viruses did not interfere with each other.

DOI

10.21608/ejar.2005.243342

Authors

First Name

SAMER M.

Last Name

ALI

MiddleName

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Affiliation

Veterinary Serum and Vaccine Research Institute, Agricultural Research Centre, Ministry of Agriculture, Dokki, Giza, Egypt

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First Name

TAUMOR N.

Last Name

MARCOSS

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Affiliation

Veterinary Serum and Vaccine Research Institute, Agricultural Research Centre, Ministry of Agriculture, Dokki, Giza, Egypt

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Orcid

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Volume

83

Article Issue

1

Related Issue

34052

Issue Date

2005-03-01

Receive Date

2004-07-20

Publish Date

2005-03-01

Page Start

439

Page End

449

Print ISSN

1110-6336

Online ISSN

2812-4936

Link

https://ejar.journals.ekb.eg/article_243342.html

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https://ejar.journals.ekb.eg/service?article_code=243342

Order

35

Type

Original Article

Type Code

1,041

Publication Type

Journal

Publication Title

Egyptian Journal of Agricultural Research

Publication Link

https://ejar.journals.ekb.eg/

MainTitle

PRODUCTION AND EVALUATION OF A COMBINED INACTIVATED VACCINE AGAINST FOOT AND MOUTH DISEASE AND RIFT VALLEY FEVER USING ISA25 OIL ADJUVANT

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Article

Created At

22 Jan 2023