Under greenhouse conditions, control of crown gall disease was tried through systemic resistance induced by organic acids, salts and bacteria. Oxalic and salicylic acids, mono-and dibasic sodium phosphate as well as Bacillus subtilis and Pseuclomonas fluorescens were used. The afore-mentioned inducers were evaluated for induced systemic resistance (ISR) in Prunus persica seedlings against Agrobacterium turnefaciens. The inducers were sprayed on peach leaves followed by inoculation with the pathogen. Salicylic acid was highly effective in controlling the disease followed by P. fluorescens, monobasic potassium phosphate and B. subtills, in a descending order. Oxalic acid, monobasic and dibasic sodium phosphate had slight or no effect. Free, conjugated and total phenolic compounds accumulated in roots of treated seedlings with the effective inducers. A positive correlation between the effectiveness of the used inducers and accumulation of phenolic compounds was recognized. Further investigations are needed on this effect as a prophylactic safe measure for crown gall control.