Three extracts of Egyptian sesban (Sesbania aegyptica Jynit) seeds were used for protection of wheat grains against Rhizopertha dominica, F. adults. The petroleum ether extract was applied to wheat grains at 6, 7, 8, 10 and 12 ml/kg, chloroform extract at 4, 6, 8, 9 and 12 ml/kg, while acetone extract was added at 4, 5, 6, 7 and 8 mVkg. After three days of exposure, the three extracts at the high concentrations caused high level of mortality and gave complete mortality (100%) after 7 days of exposure. This effect was continued up to two months of storage, then decreased gradually. The Lc_so, Ly_s values were (8 & 10), (6.5 & 16) and (6 & 12) ml/kg for petroleum ether, chloroform and acetone extracts, respectively. The Lew values of the three extracts caused high reduction in the number of F₁ progeny, no offspring was produced with Lon values. The Suction In the percentage of germination for the treated grains ranged between (12.5 % - 26 %) in comparison with control. The use of the tested extracts at the Lc_so, Ly_s levels reduced the loss in weight of wheat grains after 2 months from the treatment