The study aims to evaluate the efficiency of different irrigation systems in rationalizing irrigation water in Egyptian Agriculture, particularly in the production of wheat, through improving the production efficiency in water use by converting to modern irrigation systems and expanding wheat cultivation in more suitable areas can lower water expenditure. Hence, the main objective is to evaluate the economic efficiency of wheat production under different irrigation systems in the West of Nubariya region. The average cultivated wheat area in Nubariya is about 134.85 thousand feddans representing about 4.28% of total wheat production with an average production of 346.5 thousand tons representing 4.04% of total wheat production in the period 2005/2006 to 2019/2020. The study relied on estimating production Functions and performance efficiency, in addition to analyzing production and economic efficiency using data envelopment analysis, based on field data for a stratified random sample of wheat producers in the west of Nubariya region. The sprinkler and drip irrigation systems performed better compared to surface irrigation system in reducing the value of total costs by 19% and 33% and in achieving an increase in total revenue by 1.8% and 2%. Additionally, the application of the sprinkler and drip systems was associated with an increase in the net revenue per water unit by 414% and 551% respectively.