Due to the fact that the chicken growth hormone gene (cGH) is critical for controlling development and metabolism, there could be a link between GH polymorphisms and economic features in chickens. The objective of this study was to detect the single nucleotide polymorphisms (SNPs) in the GH and insulin-like growth factor-binding protein 2 (IGFBP2) genes, and to investigate their associations with body weight (BW). Three hundred individuals (100 birds for each commercial strains Sasso and Ross and one local breed; Baladi) were assayed. And the three primers were amplification with a total of 54 samples from three genotypes (Ross=18, Sasso=18 and Baladi=18). A total of SNPs sequenced was 138,106bp consisting of 13,265bp coding regions and 124,841bp non-coding regions. A total of 197 SNPs were identified, with 34 in coding SNPs regions and 163 in non-coding SNPs regions. The values of variation in coding regions, transitions accounted for 53% (18),26% (9) and 21% (7),while in non-coding regions were 27% (111),33% (132) and 40% (163) in Ross, Sasso and Baladi for three genes. This result is most likely due to the high, medium, and low body weights of Ross, Sasso, and Baladi breed. The higher frequency of A↔G and A↔C and lower frequency of G↔T may be related to higher body weight in the Ross strain. While, the higher frequency of A↔C, C↔T and lower G↔T may be related to lower body weight with Baladi breed. Our study confirms the analyzed three genes affecting meat production in poultry.