Wild, cultured Nile tilapia Oreochromis ni/otcus and imported mackerel Scombridae spp. are the cheapest cornmerdal consumed fishes in Egypt. Their fillet yield, chemical composition, was subjected to evaluation according to the following items: (minerals, fatty acids, cholesterol levels), microbiological and organoleptic properties. Fillets weigh, length and yield showed the highest values for imported mackerel fillets when compared with the wild and cultured Nile tilapia. Significant (P<0.05) differences in moisture, crude protein, total lipids, ash, carbohydrate % and energy calories were observed between Nile tilapia and imported mackerel, whereas non-significant (P<0.05) differences in chemical composition between wild and cultured Nile tilapia were detected. Fish that were examined in this study had more than 50% of the daily requirements of adult man from P and Mg. Cultured Nile tilapia had elevated contents of mineral (Ca, Mg, P, Fe and K), mono unsaturated fatty adds (MUM), poly unsaturated fatty adds (PUFA) as compared with the other fishes. While, the imported madcerel had the highest level of cholesterol. Non-significant (P<0.05) differences were exhibited in total bacterial count (TBC) and coliform count (CC) between the three types of fish. Staphylococcus count (SC) was not detected in all samples. Appearance, color, odour, texture and overall acceptability showed higher significant scores (P<0.05) for wild followed by cultured Nile tilapia and imported maderel, respectively.