This experiment was conducted to study the potential of using treated sewage water (TSW) for irrigation purpose and evaluate its side effect on the irrigated plant under different soil types, (loamy sand and silty loam soil). The obtained data showed that irrigation with treated sewage water TSW increased total chlorophyll significantly in wheat and radish than other irrigation sources. Conversely, total chlorophyll content decreased significantly when wheat or radish was irrigated with ground water (GW). All irrigation water sources showed no great differences in chlorophyll a/b. Carotenoids differed significantly due to irrigation water source and reached its peak when plants were irrigated with TSW. Also, irrigation with Nile water (NW) and TSW increased fresh and dry weight of wheat and radish plants significantly more than the other irrigation water sources while; they decreased significantly when plants were irrigated with agriculture drainage water (ADW). The highest fresh /dry weight ratio was obtained when plants were irrigated with NW followed by TSW. while ADW showed the lowest in this respect.