Laboratory rearing of Sesamai cretta Led. larvae on an artificial diet is very important for pest control programs. However, in some conditions such as starvation might affect some biological aspects. So in this study, the authors found that starvation of larvae for 60 hours and 72 hours led to decrease larval duration to 26.7 and 28.6, days respectively in comparison to 30.03 days for control. While, adult longevity increased. Also, pupal malformation had been dearly increased when larvae were starved for 48 hails. Pupal duration was prolonged in case of 60 hours starvation (13.7 days) comparing with 10 days for 0 hours starvation. Pupal weight was decreased when larvae were starved for 60 hours (0.1411 and 0.1238 gm for male and female, respectively). Sex ratio was determined through out different starvation periods. On the other hand, starvation of S. cretica larvae caused significantly reduction in total soluble proteins, carbohydrates, lipids and carbohydrates hydrolyzing enzymes (invertase and amylase). Also, the results showed that invertase activity was higher than amylase activity in normal S. aetica larvae.