Heating is used extensively to control some pests as well as stored-product pests. There are three temperature zones for any organisms: optimal at 25-33°C for is greatest rate of growth and reproduction, suboptimal at 33-35°C, mites able to complete their development slowly and produce offspring and Lethal >35°C eventually die, The more extreme of temperature the more quickly die with death occurring in few minutes at 45°C or hours at 50-60°C. Lethal effect of high temperature (40, 45 & 50 °C) for different exposure periods (5, 15, 30, 60, 90 &120 min.) , respectively, on survival stages of Tyrophagus putrescentiae (Shrank) was studied. Heat shock treatment reduced the number of all stages. The mean of mortality percentage increased with increasing temperature and duration. These percentage were 83, 87 & 92 % for egg, 81.8, 86.2 & 91.7 % for larva, 71.3, 82.2 & 88.7% for protonymph and 70.3, 81.5 & 86% for deuotonymph at 40, 45 & 50°C, respectively. it is notice thus mortality increased by increasing temperature and long time. Therefore all stages of the grain mite T. putrescentiae die at 50°C and 60 min exposure. At 45°C high mortality percentages occurred between mite individuals at 90 min. while treatments at 40°C and 120 min. exposure gave similar mortality percentage.