The present study aimed to investigate subacute histopathological changes induced by male albino rats after orally treatment with 320, 80 ppm butachlor 60% EC. At the end of treatment period samples of liver, kidney and stomach tissues of the two treated groups were taken and microscopally examined, then compared with tissues taken from the control group. The histopathological examination showed that both used doses affected the three examined organs, where more damages were happened in liver and stomach tissues by the low used dose and more damages were observed in kidney tissues by the high dose.