Experiment was carried out at Biahmo, Fayoum Governorate, during 2009 season. Four cucumber varieties ( Cucumis sativus L.), Xena, Sweet crunch, Nemsse and Zaeim were selected to study their sensitivity to four piercing sap sucking pests infestation {the spider mite, Tetranychus arabicus Attiah, the whitefly, Bemisia tabaci (Gennadieu), the thrips, Thrips tabaci Lindquist and the aphid, Aphis gossypii Glover} and their associated predator, the pirate bug, Orius sp. under field condition, all treatments were applied 4 times. Data revealed that Nemsse cultivar harbored the highest infestation of spider mites, with mean numbers of 77.8 individuals / 40 plants, followed insignificantly by Sweet crunch cultivar (52.5 individuals / 40 leaves), while Xena cultivar recorded the lowest infestation (18.9 individuals / 40 leaves). On the contrary Thrips sp. recorded the highest infestation in Xena cultivar with mean numbers of 205.4 individuals / 40 leaves. No significant difference in the average number was found between the different CULTIVARS for the whitefly population. Zaeim variety was more susceptible to the aphid infestation than the other varieties with a significant difference in the average number comparing to Sweet crunch and Nemsse CULTIVARS. The highest total cucumber fruit yield was obtained by Xena cultivar, followed by Zaeim, Sweet crunch then Nemsse CULTIVARS, respectively. They recorded 18.65, 16, 15.9 and 14.2 tons / feddan, respectively.