The present work was conducted to evaluate the toxicity of some plant extracts against wood borers. The obtained results showed that, average percentages of mortality of Sinoxylon sudanicum, beetles increased with increase of concentrations of different extracts of lemon grass and lantana plants. Five statistically groups were recorded for lemon grass and lantana extracts. Highest effective group (more than 70% mortality) recorded for each volatile oil extract of lantana at 4% conc. (71% mortality), acetone extract of lantana at 4% conc. (73% mortality), chloroform extract of lemon grass at 4% conc. (77% mortality) and ethanol extract of lantana 4% conc., (77% mortality). The other four groups of the mortality percentages by different extracts were ranged between1-10%, 12-15%, 26-47% and 49-65% mortality. LT50 values obtained from lemon grass extracts showed that the higher efficacy was recorded with chloroform 4%, 2% and 1% Conc. (1.47, 2.71 and 3.47 days), volatile oil 4% (3.91 days) and petroleum ether 4% (5.65 days), while the shortest LT50 values for lantana extracts were obtained from ethanol 4% (1.56 days), acetone 4% (1.62 days) and volatile oil (1.83 days). Lethal concentration toxicity estimated by lowest LC50 value for lemon grass extracts was 0.79 recorded for chloroform extract followed by 0.86 (for volatile oil), 1.31 (for petroleum ether) and 2.92 (for acetone extract), these values were recorded at the 7th day of treatment, while the lowest value of LC50 for lantana extracts was 0.001 recorded for acetone extract at 6th and 7th day followed by 0.05 for ethanol at 6th day, 0.074 for volatile oil at 7th day, 0.22 for petroleum ether at 7th day and 3.06 for chloroform at 7th day.