Peach fruit fly, Bactrocera zonata (Saunders) (Diptera: Tephritidae), has been recognized as a serious insect pest during the last decade attacking a wide range of fruits in Egypt. The potential of some insect growth regulators, Pyriproxyfen, Methoxyfenozoide and Novaluron to cause fatal hormonal disorders in immature stages, full grown larvae and 1-day old pupae, of B. zonata in sandy soil was studied under laboratory conditions. In addition, morphogenetic activity as larval-adult and pupal-adult intermediates of B. zonata resulting from IGRs treatment was recorded. Results indicated that, LC50 for full grown larvae were 0.96, 11.40 and 64.0 ppm in case of Pyriproxyfen, Novaluron and Methoxyfenozoide, respectively. The LC50 values for 1-day old pupae of B. zonata were 4.50 and 3200 ppm for Pyriproxyfen and Novaluron respectively, while Methoxyfenozoide has no fatal effect on 1-day old pupae of B. zonata. On the other hand, the EC50 values of full grown larvae were 1.31, 16.8 and 550 ppm for Pyriproxyfen, Methoxyfenozoide and Novaluron, respectively. The EC50 values for 1-day pupae were 2.80, 1450 and 5000 ppm, for the same compounds, respectively. The obtained results proved that, Pyriproxyfen is a promising candidate for the control of the peach fruit fly.