Among higher fungi, Pleurotus is well acknowledged as an economically important genus. This may be attributed to its world-wide distribution, its broad adaptability to various conditions. Pleurotus citrinopileatus has a very attractive yellow color, good culinary properties, and has highly appreciated commercial potentials in many countries. This Pleurotus type was newly introduced to Egypt from China. This investigation was carried out to determine the cultivation possibility of this new mushroom type under the domestic conditions using the cheap available agro-wastes throughout three consecutive seasons. Rice straw, wheat straw and sawdust were used as base substrates for growing media formula. Growing parameters such as spawn run (incubation time), pinheads initiation, fruit bodies development (maturation) time, yield and biological efficiency (BE%) were studied. Main chemical constituents of the P.citrinopileatus were estimated. The yielded fruit bodies were dried either by sun or oven and drying data was recorded. Spawn run time ranged from (18-28), (18- 30), (16- 26) days for first, second and third season, respectively .Fruit bodies development (maturation) were 6-8 days for all tested media. The total fresh yield ranged from 137- 393 g/ kg wet media with BE% of 38-115% for all media through the tested three seasons. The mixture of rice straw and wheat straw media gave the highest yield, while the sawdust media produced the lowest one. P.citrinopileatus fruit bodies contained 85.90- 87.37% moisture content, 22.84 – 26.01% crude protein, 2.59 – 3.23% crude fat, 7.76 – 9.06% ash and 63.77 – 65.58% total carbohydrates on dry weight basis. The fruit bodies required 35- 55 hrs. for sun drying, while they took 9 – 14 hrs for oven dehydration. Control and sulfured samples dried either by sun or oven showed superior values for rehydration ratio and sensory characteristics. According to the obtained data it could be recommended that P. citrinopileatus cultivation could be spread and encourged using the available materials in Egypt.