the current study was conducted at the experimental Farm of South Tahrir in Al-Behira governorate, Horticulture Research Station, Horticulture Research Institute (HRI), during the two successive seasons of 2016/2017 and 2017/2018. The main target of this work was to identifying the effective rate of applied irrigation at 3 rates of (400, 500 and 600 m3/fed.) combined with organic compost fertilizers at levels (0, 5, 7.5 and 10 m3/fed.) on growth yield and chemical composition of quinoa (Chenopodium quinoa Willd) plant. The obtained data showed that, application of irrigation at moderate rates (500m3) +10m3compost/fed./season) to quinoa plant recorded the maximum values of plant height, number of branches/plant, dry weight of herb/plant (g), seed weight /plant (g), seed index، protein, carbohydrates, N, P and K contents in both seasons. While, minimum values were obtained by irrigation rates 400m3/fed./seasons + 5m3compost /fed. Irrigation rate (400m3 + 10m3compost/fed./season) resulted in the highest values of saponins and phenols. While, the lowest values were obtained by irrigation rates 600m3/fed.+5m3compost/fed.