Background: Choking is an important public health problem for young children. Choking hazards are primarily associated with food, coins, and toys. The comprehensive choking-prevention effort will rely on the education of parents, teachers, and childcare workers. So, this study aimed to: Evaluate the effect of educational Program about first aid and prevention of choking for mothers of preschool-age children. Research Design: Quasi-experimental design was utilized in this study. Subjects: Included a convenience sampling of 200 mothers from outpatient clinics at Assuit university children's hospital. Tools of data collection: Three tools included Personal characteristics of mothers and their children, mothers' knowledge and practices regarding choking first aids and prevention. Results: The majority of the studied mothers (82.5%) had inefficient knowledge score regarding prevention and first aid of chocking while only 17.5% of them had efficient knowledge before mobile education compared to 99.5 % of them had efficient mean knowledge after mobile education. There were statistically significant differences between the mother's knowledge and reported practice pre and post-Mobile-based program application for choking prevention (P value <0.001). Conclusion: Tthe mother's knowledge and reported practices regarding choking prevention were improved after the implementation of the mobile-based program. Recommendations: Health promotion programs through nurses using new educational technology about choking first aid and prevention should be directed to mothers, children's caregivers, and teachers in all pediatric care sittings and nursery schools.