Background: Autism is a syndrome that manifests itself in the first three years of life and is characterized by communication difficulties and recurrent interests and behaviours.The aim of the study: To identify the effectiveness of cognitive-behavioural training program on the enhancement of affective communication skills for autistic children.Subjects and Method: Quasi-experimental research design was used. The study subjects were consisted of (62) autistic children randomly distributed equally between the experimental and control groups. The study conducted at the child psychiatric outpatient clinic of the psychiatric mental health hospital in Assiut city, Egypt . Two tools were utilized in this study; Tool I: A structured interview questionnaire, which includes two parts, part I: personal data of autistic children, part II: socioeconomic evaluation scale to determine the family's socioeconomic position. Tool II: Autistic behavioural rating scale. Results: There was an equivalent in the mean scores of the studied sample (experimental & control groups) in the four dimensions (social, communicative, behavioural, and motor-sensory) of the autistic behavioural rating scale before the cognitive training program,while there was increasing in the four dimensions among the experimental group with a statistically significant difference post the cognitive behavioural training program. Conclusion: The cognitive-behavioural training program was very effective for improving social, communicative,behavioural and motor-sensory skills of autistic children. Recommendation:Continues educational family programs regularly are suggested to increase the capacity of autistic children to engage, communicate, utilize multiple senses and employ different techniques of interactions with others, as well as increase parental perception and care of the autistic children .