Abstract Aim of the studyTo investigate the prevalence of modifiable and non modifiable risk factors associated with acute stroke Retrospective research design was used. This study was carried out at Emergency department at Assiut University Hospitals .The sample of this study was consisted of 60 patients, admitted to Emergency department with acute stroke. Tool used in this study consisted of an assessment sheet developed by the researcher for identifying the risk factors commonly associated with types of acute stroke. This tool comprised two main parts, part I: - Assessment of socio-demographic and clinical data. part II: - assessment of acute stroke risk factors. The main results: revealed significant difference between both groups regard type of acute stroke (p < 0.03). The result of the current study revealed that majority of the study sample was old age with no significant difference. Also majority of the study sample were females in both ischemic and hemorrhagic acute stroke. The current study revealed that hypertension is the first and major cause of acute ischemic or hemorrhagic stroke. Risk factors associated with acute stroke show no significant difference between both group with (46.66%) for hypertension, (10.0%) for DM, (15.0%) for obesity and IHDs. conclusion: age and hypertension are the most significant risk factors for incidence of stroke the study sample. Recommendations: - Based on the study it is recommended to develop educational programs for raising public awareness of stroke risk factors and warning signs and identifying those at risk of stroke