Abstract Hospitalization presents specific stress over those associated with illness. Privacy, independence and social support are reduced. Therefore, the aim of the study was to assess hospitalization related stress and social support among psychiatric patients and explore relationship between them. Patients and method: Sample included all patients admitted to the psychiatric inpatient units for six months from July to December 2013. Three tools were utilized to measure the variables of the study: Socio-demographic data sheet, Hospital Stress Rating Scale and Multidimensional Scale of Perceived Social Support Results revealed that, being hospitalized far away from home and being in the hospital during holidays were the major reasons for hospital related stress experienced by psychiatric patients.41.9 % of psychiatric patients had moderate level of hospital stress and 22.9% of them had low level of social support. Conclusion: More than one third of the psychiatric patients had moderate level of hospital stress and nearly one quadrant of them had low level of social support. The results showed that there was no statistically significant relation between hospital stress and social support. Recommendations: Psycho educational programs are essential to educate psychiatric patients how to deal with hospitalization related stress and increase social support for them.