Abstract
Venous thromboembolism (VTE) is one of the most common preventable causes of death in trauma patients. Therefore, mechanical prophylaxes Sequential Compression Devices (SCDs) are important part for prevention of VTE in trauma patient. Aim: to determine the effect of sequential compression devices on venous thromboembolism prevention in mechanically ventilated trauma victim.  The Researcher usedquasi-experimental research design to conduct this study.This research was performed in the trauma ICU at Assiut University Hospital. Sample: A convenient sample of sixty patients entered to trauma ICU. They were split into two groups at random: in control and study group (30 patients each).Tools: Tool I: Modified patient assessment tool, Tool II: - patients' outcomes Assessment sheet. Results of the present study mentioned that study group subjects had lower incidence of VTE (6.66% vs 36.7% among control group), also lower mean length of stay (7 days vs 13.6 days for control group), and lower mean days of MV in study subjects than control group with P=0.000. Conclusion: combination of mechanical and pharmacological prophylaxis help in improve outcomes by reducing  incidence of VTE, length of stay and mechanical ventilator days Recommendations: Developing strategies that necessitate training healthcare providers to enhance  performance, improve patient' outcomes, and fulfill effectiveness of mechanical prophylaxis devices.