Abstract Background: Psychological morbidity is common in women with urinary incontinence and is likely to result directly from the impact on quality of life. The study aimed to: - evaluate the psychological distress and quality of life among female stress urinary incontinence patients pre and post non-invasive laser therapy &assess the efficacy of a novel minimally invasive non-ablative laser treatment for female SUI. (Stress Urinary Incontinence) Design: - This is prospective non randomized study. Sample: the study was carried out at Urology Department, Sohag University Hospital on 10 % (32 patients) of the female patient. Tools: - International Consultation on Incontinence Questionnaire – Urinary Incontinence Short Form (ICIQ-UI SF), Kessler Psychological Distress Scale (K10), and (Incontinence Quality of Life) I-QOL. Results: - The majority of the participant have moderate and severe psychological distress. There were statistically significant difference between levels of psychological distress at pre and post Laser therapy among studied patient; also, quality of life domains at pre, and post laser therapy among studied patient. Conclusions: Stress urinary incontinence can cause psychological distress for majority of patients and also, have a negative impact on their quality of life. Recommendations: - psychological intervention beside laser therapy will be improve psychological distress and QOL among SUI.