Abstract
Background: Sickle cell anemia (SCA) is a hereditary chronic genetic blood. Aim: To evaluate the impact of nursing instructions protocol on health promotion life style for patients with sickle cell anemia. Research design Quasi-experimental research design. Setting: New Valley (El Kharga general hospital). Patient and Methods Thirty adult patients with sickle cell anaemia. Tools: "Structured interview patient questionnaire". Tool (II): Health promotion Model – Instruments to measure health promoting lifestyle. Results: More than half of the studied sample was male with mean age (27.96±8.84). There was a highly statistically significant difference in the Patients' health promotion was increased after the implementation of the booklet; particularly in the areas of the health responsibility, physical activity, nutrition and Non-significant difference in interpersonal relations. Conclusion: The study findings supported all research hypotheses as it had been proven that the nursing instruction protocol had statistical significant effect on minimizing pain and improving health promotion lifestyle. Recommendations: It is important to educate patients about how to modify life style to healthy life, relieve and manage sickle cell anemia complications.