Background:- Painful medical procedures in childhood may have long-term negative effects on development and future tolerance of pain. Evidence recommends that a significant number of children get less than optimum management of procedure-related to pain. So this study aimed to assess effect of cough trick method on pain intensity during venipuncture procedure among hospitalized children. Quasi experimental research design was used in this study. Subjects included 60 hospitalized children recruited from emergency unit as well as medical and hematology units in Assuit University Children Hospital. They were selected randomly and divided into two groups: study & control groups. Two tools were used for gathering necessary data which included, tool (1) A structured questionnaire sheet for personal and medical data, tool (II) Facial Pain Scale- Revised (FPS- R scale) that was used to assess pain intensity during venipuncture. Results showed that, there were a statistically significant difference in pain intensity in study group compared to control group (1.00 ± 2.15 & 7.67 ± 1.75). Conclusion cough trick was effective in reducing pain intensity during venipuncture. Therefore, it is recommended that the use of educational training program for nurses about using cough trick as non- pharmacological intervention to reduce pain among children