Stress and temporomandibular joint (TMJ) are often linked to each other. The symptoms of stress manifest in physical ways, often leading to a TMJ disorders and can cause jaw tension or pain. Physiotherapy treatment is very effective in relieving and managing temporomandibular joint disorders (TMJDs), even when the symptoms are long-standing and severe. Aim: To evaluate the effect of nursing psychological support and teaching physiotherapy guideline on improving pain level for patients with TMJDs. Research design: Pre/post-test research design was utilized on 50 adult patients with TMJDs. Setting: The study was conducted in the maxillofacial surgery outpatient clinic at Assiut University Hospital. Tools: Three tools were used, I) Structured questionnaire, II) psychological state assessment and III) universal pain assessment. Results: About half of the study group their age range between 18-29 years old, with mean of (29.12±9.82) and about three quarter were females. There were statistically significant differences for the study group as regard psychological state and universal pain assessment. Conclusion: It was concluded that nursing psychological support and teaching physiotherapy are an important factors in the treatment of temporomandibular joint disorders. Recommendations: A written teaching guideline should be available for patients in simplified term and containing simple pictures.