Background, Bariatric surgery includes a variety of procedures performed on people who have obesity. The study aimed to investigate the impact of nursing guidelines among bariatric surgery patients on minimizing the postoperative complications for patients with bariatric surgery. Research design, Quasi-experimental research design was utilized in this study. Sample, the study was conducted on a convenient sample of 50 adult patients with bariatric surgery who selected randomly (25 - study group and 25 - control group). Setting, data were collected from plastic surgery department at Assiut University Hospital. Tools, data were collected through two tools; patient informational assessment sheet and postoperative complications follow up sheet. Results, this study concluded that more than half of the sample in the study group were females. While the majority of the sample in control group 92% were females and 52.0 %were married. There was statistically significant difference as regarded pre and postoperative score for level of knowledge of study group about bariatric surgery except important of the efficiency of vital signs, knowledge about postoperative complications, an exercise carried out and good diet after the operation. Conclusion, there were significant differences improvements throughout the implementation of nursing guidelines among the study group. Recommendation, the study recommended that pamphlets and simple illustration booklet should be available for patients illiterate to with simple explain how to safely live after bariatric surgery.